Comparative study between two groups of participants,both groups receiving different drug combinations during spinal anesthesia for elective gynecological surgeries.

Comparison of intrathecal fentanyl and dexmedetomidine as adjuvants to hyperbaric bupivacaine for elective gynecological surgeries : A double blind controlled study. - NIL

Status

Active, not recruiting

Phases

Phase 2

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2025/02/080174

Enrollment

142

Registered

2025-02-10

Start date

Unknown

Completion date

Unknown

Last updated

2025-03-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: O- Medical and Surgical

Interventions

Intervention1: Injecting intrathecal 5mcg dexmedetomidine as adjuvant to 2.7ml hyperbaric bupivacaine in patients undergoing elective gynecological surgeries.: Onset and duration of sensory and motor

Eligibility

Inclusion criteria

Inclusion criteria: 1. 18-60 years female patients with physical status 1 and 2 according to the American Society of Anaesthesiologists(ASA). 2. Patients undergoing Total abdominal hysterectomy (TAH), Vaginal hysterectomy (VH) and Myomectomy. 3. Providing written informed consent.

Exclusion criteria

Exclusion criteria: 1. Patient refusal. 2. ASA grade 3 and 4. 3. Emergency surgeries. 4. Patients with motor and/or sensory deficit. 5.Patients with anticipated difficult airway. 6.Patients having compromised cardiac,pulmonary,hepatic and renal functions. 7. Patients with seizure disorders. 8. Patients having coagulation disorders. 9. Localised skin infection at the site of injection. 10. Patients having known allergy to drugs used in this study.

Design outcomes

Primary

Measure	Time frame
Duration of sensory and motor block and hemodynamic changes.Timepoint: Intraoperative.	—

Secondary

Measure	Time frame
Onset time to reach peak sensory and motor block and assessment of adverse effect.Timepoint: Postprocedural.	—

Countries

India

Contacts

Public ContactDr Dibyendu Garai

Institute of Post Graduate Medical Education And Research, Kolkata

dibyendugarai.dg@gmail.com9433181485

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026