Health Condition 1: T603- Toxic effect of herbicides and fungicides
Conditions
Interventions
Intervention1: N ACETYLCYSTEINE: We plan to give intravenous N acetylcysteiene 150mg per kg in 500ml 5 percentage dextrose for 1 hour followed by 50mg per kg in 500 ml 5 percentage dextrose for 4 hou
Sponsors
Postgraduate Institute OF Medical Education and Research
Eligibility
Inclusion criteria
Inclusion criteria: patients aged morethan 18 years with history of ingestion (oral route) of paraquat till 5 days
Exclusion criteria
Exclusion criteria: 1)only inhalational and dermal exposure to paraquat 2)pregnant females 3)chronic lung disease (COPD&ILD) 4)chronic kidney disease 5) COVID-19-Positive patients 6)paracetamol poisoning where N acetylcysteine is to be given as treatment 7)multiple poisonous compounds consumption like organophosphorus and paraquat poisoning.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| prevention acute respiratory distress syndrome and reducing its severityTimepoint: after 14 days, the patient will be assessed for the organ failure or at the patient death for mortality | — |
Secondary
| Measure | Time frame |
|---|---|
| 1)reducing the incidence of acute kidney injury 2)reducing occurrence of acute liver injury 3)reducing mortality in 14 daysTimepoint: 14 days | — |
Countries
India
Contacts
Public ContactDr Saurabh C Sharda
Postgraduate Institute Of Medical Education and Research, Chandigarh
Outcome results
None listed