Evaluation of relief of pain after operation between two types of regional anaesthesia technique (external oblique intercostal block versus oblique subcostal transversus abdominis plane block) for a special type of cut in the abdominal wall known as modified Makuuchi incision

External oblique intercostal block vs Oblique subcostal transversus abdominis plane block for postoperative pain management in surgeries with modified Makuuchi incision- A Randomised Controlled Study (OBLIQUES - -

Status

Active, not recruiting

Phases

Phase 2

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2025/02/080148

Enrollment

Registered

2025-02-07

Start date

Unknown

Completion date

Unknown

Last updated

2025-03-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: K87- Disorders of gallbladder, biliarytract and pancreas in diseases classified elsewhere

Interventions

Intervention1: External Oblique Intercostal (EOI) block: Ultrasound guided identification of plane between External oblique and Intercostal muscles, just medial to anterior axillary line, will inject

Eligibility

Inclusion criteria

Inclusion criteria: 1. Patients undergoing elective abdominal surgeries with modified Makuuchi incision or reversed L- shaped incision. 2. American Society of Anaesthesiology Physical Score (ASA-PS) score of I - III

Exclusion criteria

Exclusion criteria: Patients requiring postoperative mechanical ventilation. Contraindications to spinal anaesthesia Contraindications to study medication Documented obstructive sleep apnea Patients with life threatening arrhythmias Patients with left ventricular ejection fraction less than 40% Coagulopathy Pre Existing neurological illness Significant liver dysfunction (liver enzymes more than 3 times normal) Significant renal dysfunction (creatinine more than 2 times normal) Psychiatric illness Opioid abuse Patients receiving systemic opioids for chronic pain within last 30 days

Design outcomes

Primary

Measure	Time frame
24 hours intravenous morphine consumption in mgTimepoint: 24 hours intravenous morphine consumption in mg	—

Secondary

Measure	Time frame
1. 48-hours and 72-hours intravenous morphine consumption in mg 2. QOR-15 score at postoperative day 1 and postoperative day 3 3. Postoperative rescue fentanyl requirements in mcg in the first 48 hours 4. Numeric Rating Scale (NRS) 5. Modified Ramsay Sedation Score 6. NRS on first ambulation 7. NRS on coughing 8. Postoperative respiratory depression 9. Time to enteric resumption 10. Time to ambulation 11. Time to flatus pass 12. Postoperative nausea and vomiting at the above mentioned time points 13. Postoperative pruritus at the above mentioned time points 14. Patient satisfaction score 15. Length of hospital stay Timepoint: At rest on arrival at the ICU (T0); 3 hours (T1); 6 hours (T2); 12 hours (T3); 24 hours(T4); 48 hours (T5); 72 hours (T6)	—

Measure

Time frame

1. 48-hours and 72-hours intravenous morphine consumption in mg 2. QOR-15 score at postoperative day 1 and postoperative day 3 3. Postoperative rescue fentanyl requirements in mcg in the first 48 hours 4. Numeric Rating Scale (NRS) 5. Modified Ramsay Sedation Score 6. NRS on first ambulation 7. NRS on coughing 8. Postoperative respiratory depression 9. Time to enteric resumption 10. Time to ambulation 11. Time to flatus pass 12. Postoperative nausea and vomiting at the above mentioned time points 13. Postoperative pruritus at the above mentioned time points 14. Patient satisfaction score 15. Length of hospital stay Timepoint: At rest on arrival at the ICU (T0); 3 hours (T1); 6 hours (T2); 12 hours (T3); 24 hours(T4); 48 hours (T5); 72 hours (T6)

—

Countries

India

Contacts

Public ContactAngshuman Rudrapal

Tata Medical Center

angshunitya@gmail.com7980006561

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026