Health Condition 1: C921- Chronic myeloid leukemia, BCR/ABL-positive
Conditions
Interventions
Intervention1: Hormone profile including TSH, T3, T4, FSH, LH, Prolactin, testosterone, estradiol, progesterone, DHEAS, cortisol, vitamin D3 and PTH: Hormone profile will be done at the time of diagno
Sponsors
Vardhman Mahavir Medical College and Safdarjung Hospital
Eligibility
Inclusion criteria
Inclusion criteria: Patients with newly diagnosed CML above 18 years of either sex planned for imatinib therapy will be included in the study.
Exclusion criteria
Exclusion criteria: Patients less than 18 years of age, those having baseline hormonal dysfunction as determined by history and examination, patients planned for a second generation TKI like dasatinib or nilotinib and those not willing to participate in the study.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Effects of imatinib on the thyroid function, adrenal function and reproductive hormones of patients with chronic myeloid leukemiaTimepoint: baseline and after 1 year of imatinib treatment | — |
Secondary
| Measure | Time frame |
|---|---|
| Effects of imatinib on the bone metabolism of patients with chronic myeloid leukemiaTimepoint: baseline & after 1 year of imatinib treatment | — |
Countries
India
Contacts
Public ContactDr Ankur Jain
Vardhman Mahavir Medical College and safdarjung hospital
Outcome results
None listed