Comparing Pain After Single-Visit Root Canal Treatments Using New Curcumin Sealers vs Traditional Sealers in Infected Teeth: A Study

Comparative Analysis of Postoperative Pain in Single-Visit Endodontic Treatment using CurowhiteTM Enhanced Sealers versus Zinc Oxide Eugenol Sealer in mandibular premolars: A Randomized Controlled Trial - NIL

Status

Active, not recruiting

Phases

Phase 3

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2025/02/080129

Enrollment

128

Registered

2025-02-07

Start date

Unknown

Completion date

Unknown

Last updated

2025-03-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Interventions

Intervention1: GROUP 2 Zinc oxide & Curowhite 1:1 ratio with eugenol: Zinc oxide powder and curowhite powder will be taken in equal ratio and mixed with eugenol liquid to get root canal sealer consist

Eligibility

Inclusion criteria

Inclusion criteria: Age between 18 and 65 years Single rooted mandibular premolar teeth requiring single-visit endodontic treatment Teeth with or without periapical lesions Absence of alterations causing a significant increase in preparation time.

Exclusion criteria

Exclusion criteria: • Presence of pain in more than one tooth in the same quadrant. • Teeth with open apices. • Presence of systemic diseases. • Missing opposing teeth or cracked teeth. • Pregnant patients.

Design outcomes

Primary

Measure	Time frame
Incidence and intensity of postoperative pain will be assessed at 24, 48, and 72 hours and 1 week. Participants will complete a Visual Analog Scale (VAS) questionnaire for pain intensity. Medication usage data will be collected through patient recall and medication logs. Adverse events will be documented and reported. Timepoint: 24, 48, and 72 hours patient will be reviewed through phone call and after 1 week - clinical review will be done	—

Measure

Time frame

Incidence and intensity of postoperative pain will be assessed at 24, 48, and 72 hours and 1 week. Participants will complete a Visual Analog Scale (VAS) questionnaire for pain intensity. Medication usage data will be collected through patient recall and medication logs. Adverse events will be documented and reported. Timepoint: 24, 48, and 72 hours patient will be reviewed through phone call and after 1 week - clinical review will be done

—

Secondary

Measure	Time frame
Periapical healing using PAI scoreTimepoint: 1 week, 6 months and 1 year	—

Countries

India

Contacts

Public ContactDr Anand Sherwood I

geethdeepika@gmail.com8015508427

Outcome results