Health Condition 1: L400- Psoriasis vulgaris
Conditions
Interventions
Intervention1: Individualized Homoeopathic medicines will be remedies that will be prescribed and administered orally in centesimal potencies (6c, 30c, 200c, 1M, 10M, and 50M) with necessary repetitio
Sponsors
National Homoeopathy Research institute in Mental health Kottayam Kerala India
Eligibility
Inclusion criteria
Inclusion criteria: Age between 18- 60 years, all genders. Clinically diagnosed with a mild, moderate case of psoriasis vulgaris ( according to the classification of psoriasis severity) with increased IL-6biomarker.
Exclusion criteria
Exclusion criteria: Pregnant and lactating mothers Severe form of psoriasis vulgaris ( according to the classification of psoriasis Severity ) Cases with psoriatic arthritis. Evidence of skin conditions other than psoriasis that would interfere with evaluations of the effect of study medication on psoriasis Participants are on systemic immune-suppressive therapy or any treatment below six months. The patient has generalized pustular Psoriasis or erythrodermic Psoriasis with Significant functional impairment and high levels of distress.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Changes in the IL-6 inflammatory biomarkers baseline after the 6th month and at the 12th month after the intervention in both the verum and placebo groupsTimepoint: Changes in the IL-6 inflammatory biomarkers baseline after the 6th month and at the 12th month after the intervention in both the the verum and placebo groups | — |
Secondary
| Measure | Time frame |
|---|---|
| Changes in the PASI score before and after treatment before and after intervention in both verum and placebo groupsTimepoint: Baselin,Every 3, 6, 9 and 12 months;Changes in the Dermatology Life Quality Index (DLQI) score before and after intervention in both verum and placebo groupsTimepoint: Baseline, Every 3,6,9 and 12 months;Outcome related to impact in daily living (ORIDL) score after intervention in both verum and placebo groupsTimepoint: Every 3,6,9 and 12 months | — |
Countries
India
Contacts
Public ContactDr. Sitharthan.R.
Kerala university of Health Sciences
Outcome results
None listed