Health Condition 1: O- Medical and Surgical
Conditions
Interventions
Intervention1: intravenous Dexmedetomidine 1mcg/kg: intravenous infusion of dexmedetomidine 1mcg/kg in 100 ml NS over 15 to 20 minutes 5 minutes before induction of general anaesthesia
Control Interve
Sponsors
Smt Bhikiben Kanjibhai Shah Medical Institute and Research Centre
Eligibility
Inclusion criteria
Inclusion criteria: Patients willing to give written and informed consent male and females of age group 18 to 55 years of age patients belonging to ASA physical status 1 and 2 patients posted for elective surgeries under general anaesthesia
Exclusion criteria
Exclusion criteria: patients unwilling to participate in the study patients with crdiovascular, cerebrovascular, hepatic and renel diseases patients having arrhytmias or heart block psychiatric patients pregnancy and lactating patients patients taking beta blockers history of allergy to the study drugs BM! more than 30 patients with ASA physical status of 3 and above patients with suspected difficult airway and Mallampatti grade 3 and 4
Design outcomes
Secondary
| Measure | Time frame |
|---|---|
| to study sedation status using RAMSAY sedation scoreTimepoint: post operatively for every 30 minutes till RAMSAY sedation score of 2 is achieved | — |
Primary
| Measure | Time frame |
|---|---|
| to study hemodynamic response during laryngoscopy and endotracheal intuabtionTimepoint: baseline after administration of the test drug after induction at laryngoscopy and intubation at 1 min after intubation at 3 mins after intubation at 5 mins after intubation | — |
Countries
India
Contacts
Public ContactDr Sara Mary Thomas
Smt. Bhikiben Kanjibhai Shah Medical Institute and Research Centre
Outcome results
None listed