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Crystalloid vs Colloid Preloading in lower limb orthopedic Surgery under spinal Anaesthesia a Study to Compare the Hemodynamic Changes

A Study to Compare the Hemodynamic Changes in Patients Undergoing Lower Limb orthopaedic Surgeries under Spinal Anaesthesia When PreLoaded with Crystalloid vs Colloid. - NIL

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2025/02/080064
Enrollment
40
Registered
2025-02-07
Start date
Unknown
Completion date
Unknown
Last updated
2025-03-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: O- Medical and Surgical

Interventions

Intervention1: Inj. RL intravenously at the rate of 10ml/kg.: Patient will be preloaded with 10ml/kg of ringer lactate solution over a period of 20 minutes just prior to the administration of final an

Sponsors

Smt Bhikiben Kanjibhai Shah Medical Institute and Research Cen
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: 1)The patients belonging to ASA-I and ASA-II. 2)Age Group from 18 to 35 years. 3)Patients undergoing LSCS. 4)Duration of surgery from 3 to 3.5 hours.

Exclusion criteria

Exclusion criteria: A)All contraindications for spinal anaesthesia like: Patients refusal Local infections Spinal deformities Bleeding disorders Increased intracranial tension Systolic blood pressure less than 100mmHg. B)Age less than 18 years or more than 60 years. C)Concomitant diseases – diabetes mellitus, hypertension, heart diseases, obesity. D)Patients other than ASA-I and ASA-II.

Design outcomes

Primary

MeasureTime frame
his study will help us to know that which out of two intravenous solutions (1) Colloid or (2)Crystalloid is a better preloading solution to achieve the stable hemodynamics during lower limb orthopaedic surgeries.Timepoint: Heart rate Systolic and diastolic blood pressure and mean arterial pressure will be monitored every 2 minutes for the first 10 minutes and then every 5 minutes till the next hour and then every 15 minutes till the end of surgery

Secondary

MeasureTime frame
Requirement of vasopressor.Incidence of nausea and vomiting.Incidence if allergic reactions Timepoint: will be monitored every 2 minutes for the first 10 minutes and then every 5 minutes till the next hour and then every 15 minutes till the end of surgery

Countries

India

Contacts

Public ContactDr Priya Kishnani

Smt. Bhikiben Kanjibhai Shah Medical Institute and Research Centre

drpriya0809@gmail.com9898076139

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026