Skip to content

Effect of Paracetamol and Ibuprofen infusion on pain in patient posted for Abdominal Hysterectomy surgery with laparoscope

A Prospective Randomized Comparision of Intravenous Paracetamol and Ibuprofen as Preemptive Analgesia in Total Laparoscopic Abdominal Hysterectomy - NIL

Status
Active, not recruiting
Phases
Phase 4
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2025/02/080056
Enrollment
88
Registered
2025-02-07
Start date
Unknown
Completion date
Unknown
Last updated
2025-03-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: N72- Inflammatory disease of cervix uteri Health Condition 2: N719- Inflammatory disease of uterus, unspecified

Interventions

Intervention1: Intravenous Paracetamol and Ibuprofen in Laparoscopic Abdominal Hysterectomy: 1000 mg Paracetamol infusion intravenous compared with 400 mg Ibuprofen infusion intravenous 15 minutes pre

Sponsors

RNT Medical College Udaipur Rajasthan
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: 1) Patients of ASA grade I-II 2) Patients scheduled for laparoscopic abdominal hysterectomy surgeries

Exclusion criteria

Exclusion criteria: 1) Lack of patient consent 2) Drug dependence 3) History of long-term NSAIDs and opioid analgesic use 4) Patients allergic to ibuprofen and paracetamol 5) Patients with diabetes or other neuropathic diseases 6) History of gastrointestinal bleeding, peptic ulcer or inflammatory bowel disease, asthma 7) Patients with severe hepatic or renal failure 8) Patients weighing less than 40 Kg

Design outcomes

Primary

MeasureTime frame
Post operative analgesiaTimepoint: 24 hours post-operatively

Secondary

MeasureTime frame
1)hemodynamic changes 2)the time to first analgesic requirement and total tramadol consumption 3)Adverse effectsTimepoint: 24 hours post-operatively

Countries

India

Contacts

Public ContactDr Maneesh Meena

RNT Medical college Udaipur Rajasthan

dr.rgehlot.2010@gmail.com9468694902

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026