Advanced-PRF(A-PRF) and Titanium-PRF(T-PRF) in maxillary sinus lift

A Comparative Evaluation of Advanced PRF (A-PRF) And Titanium PRF (T-PRF) in Maxillary Sinus Augmentation Through Crestal Approach in Implant Placement - An In Vivo Study - NIL

Status

Active, not recruiting

Phases

Phase 2Phase 3

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2025/02/080033

Enrollment

Registered

2025-02-07

Start date

Unknown

Completion date

Unknown

Last updated

2025-03-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: K063- Horizontal alveolar bone loss

Interventions

Intervention1: Titanium PRF: Titanium PRF (T-PRF) is a modified form of PRF that is prepared by blood centrifugation in titanium tubes at 2800pm for 12 min. As compared to A-PRF, T-PRF is more tightly

therefore, the resulting fibrin is more polymerized. Both the PRFs will be mixed in a sterilized mixing well with Bovine porous bone material Bio-Oss Bone Graft as it is highly osteoconductive, leadin

Eligibility

Inclusion criteria

Inclusion criteria: Patients willing for voluntary participation & have signed informed consent for the described procedure Patients having good physical and mental health and well formed or moderately formed residual alveolar ridge Systemically healthy subjects Patients requiring Sinus augmentation prior to placement of implant Patients well motivated for implant therapy and maintaining good oral hygiene Patients requiring bilateral sinus lift Bone height between 4 to 6 mm

Exclusion criteria

Exclusion criteria: Immunocompromised patients Grafted site previous or during implant placement Patients of chronic and aggressive periodontitis Flapless procedures Alcohol or drug abuse Psychologically compromised patients Patients with temporomandibular disorders severe residual ridge resorption orofacial tumors and gross facial deformity mucositis radiation therapy parafunctional habit Patients with active diseases of the implant bed example residual cysts Cancer Patients ongoing chemotherapy Patients on steroid therapy Severe Metabolic Diseases Immunocompromised patients Abnormal Platelet Function Bisphosphonates Therapy

Design outcomes

Primary

Measure	Time frame
The outcome of the study will help in comparing the formation of bone density using TPRF and APRF in maxillary sinus augmentationTimepoint: 6 months	—

Secondary

Measure	Time frame
Thicker bone density and good postoperative healingTimepoint: 6 months	—

Countries

India

Contacts

Public ContactKratika Rastogi

Sardar Post Graduate Institute of Dental and Medical Sciences

drlovebhatia12@gmail.com9451833111

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026