To know intraoperative brain relaxation and postoperative recovery using TIVA with propofol vs Desflurane anaesthesia following craniotomy in supratentorial tumours

Effect of total intravenous anaesthesia using propofol versus desflurane anaesthesia on intraoperative brain relaxation and postoperative recovery following craniotomy for supratentorial tumours-a randomised controlled trail - Nil

Status

Active, not recruiting

Phases

Phase 4

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2025/02/080013

Enrollment

Registered

2025-02-06

Start date

Unknown

Completion date

Unknown

Last updated

2025-03-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: - Health Condition 2: C718- Malignant neoplasm of overlappingsites of brain

Interventions

Intervention1: Desflurane: Intraoperative brain relaxation with Desflurane and postoperative recovery Dose and frequency -adjusted according to the BIS SCORE route -inhalational Total duration -surge

Eligibility

Inclusion criteria

Inclusion criteria: 1.Patients willing to give informed written consent 2.Patients of age group 18-60 yrs undergoing craniotomy for supratentorial tumor under general anesthesia 3.Patients belonging to ASA 1-3

Exclusion criteria

Exclusion criteria: 1. Patients not willing to give informed written consent 2. Patients undergoing emergency craniotomies under general anesthesia 3. Mentally retarded patients

Design outcomes

Primary

Measure	Time frame
Scale on intraoperative brain relaxationTimepoint: Baseline to 135min after induction of anesthesia	—

Secondary

Measure	Time frame
SOMCT Postoperative return of cognitive function Timepoint: Baseline to 135min after induction of anesthesia	—

Countries

India

Contacts

Public ContactMahima

Bangalore medical college and research institute Bangalore 560002

sandyaraghu@gmail.com9972212417

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026