Health Condition 1: M00-M99- Diseases of the musculoskeletal system and connective tissue
Conditions
Interventions
Intervention1: DEXTROSE PROLOTHERAPY,
CORTICOSTEROID INJECTION,
NORMAL SALINE: Group A- Patients will receive a single dose of (5%) dextrose prolotherapy injection (5ml) perineurally
Group B- Patients
Sponsors
All India Institute of Medical Sciences Bhubaneswar Odisha
Eligibility
Inclusion criteria
Inclusion criteria: 1.Patients aged above 18 years 2.Patients with Nocturnal paresthesia, symptomatically getting relief after shaking the hands. 3.Pain, paresthesia or sensory symptoms in the area of the median nerve over the thumb and finger. 4.Symptoms longer than 4 weeks duration. 5.Numbness in sensory distribution of median nerve. 6.Weakness with atrophic change of median nerve innervated thenar muscles. 7.Phalen test +, and or Tinel Sign +.
Exclusion criteria
Exclusion criteria: 1.Pregnancy 2.H/O of polyneuropathy, brachial plexopathy, thoracic outlet syndrome. 3.H/O Inflammatory arthritis, Type 2 DM, Rheumatologic disorder. 4.Previous h/o CS Injection, Skin infection on injection site, trauma or neoplasm at injection site, hypersensitivity to corticosteroid. 5.Current warfarin use.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| 1.To measure pain relief following perineural injections of dextrose prolotherapy and corticosteroid in Carpal Tunnel Syndrome.Timepoint: 1. 0 weeks (V0) 2. 6 weeks (V1) 3. 12 weeks (V2) | — |
Secondary
| Measure | Time frame |
|---|---|
| 1.To measure functional improvement following perineural injections of dextrose prolotherapy and corticosteroid in Carpal Tunnel Syndrome.Timepoint: 2 years;To measure the change in quality of life following perineural injections of dextrose prolotherapy and corticosteroid in Carpal Tunnel Syndrome.Timepoint: 2 years | — |
Countries
India
Contacts
Public ContactDr Apurba Barman
AIIMS Bhubaneswar
Outcome results
None listed