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To compare two drugs to be given before Spinal Anaesthesia to avoid post operative Nausea and Vomiting.

A Comparative study of efficacy of Prophylactic Ondansetron Versus Dexamethasone In Prevention Post Operative Nausea and Vomiting In Patients Receiving Intrathecal Opioids - NIL

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2025/02/079971
Enrollment
120
Registered
2025-02-06
Start date
Unknown
Completion date
Unknown
Last updated
2025-03-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: O- Medical and Surgical

Interventions

Intervention1: Ondansetron 4 mg intravenous: Ondansetron 4 mg is Serotonin 5- HT3 Receptor antagonist given 10 minutes before Spinal Anaesthesia, Duration of action 8-10 hrs Control Intervention1: Dex

Sponsors

Shreyash Gosavi
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: ASA grade 1&2, Posted for lower abdomen urology lower limb surgeries under Spinal Anaesthesia using Opioid as additive

Exclusion criteria

Exclusion criteria: Patient not giving consent, having cardiovascular and renal diseases, patient allergic to any of study drugs , patient requiring General anaesthesia, expected of having major blood los

Design outcomes

Primary

MeasureTime frame
Changes in occurence of post operative Nausea and Vomiting after using prophylactic ondansetron or dexamethasone in patients receiving intrathecal OpioidsTimepoint: Changes in occurence of post operative Nausea and Vomiting in Post operative period at 60 min, 120 min, 180 min, 240 min, 300 min, 360 min.—

Secondary

MeasureTime frame
To study various rescue medication required to treat post operative Nausea Vomiting in patients receiving intrathecal OpioidsTimepoint: Rescue medication required for post operative Nausea Vomiting after 60 minutes post operative, 120 minutes, 180 minutes, 240 minutes, 300 minutes, 360 minutes—

Countries

India

Contacts

Public ContactDr Kundan Gosavi

Grant Government Medical College JJ Hospital

kundangiri@rediffmail.com9221461101

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026