A Randomized Control Trial Comparing Reverse Bone Grafting combined with Core Decompression and Core Decompression alone in patients diagnosed with Avascular Necrosis of Femoral Head

A Randomized Control Trial Comparing Reverse Bone Grafting and Core Decompression in Avascular Necrosis of Femoral Head. - NIL

Status

Recruiting

Phases

Phase 2

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2025/02/079967

Enrollment

Registered

2025-02-06

Start date

Unknown

Completion date

Unknown

Last updated

2025-09-15

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: M873- Other secondary osteonecrosis Health Condition 2: O- Medical and Surgical

Interventions

Intervention1: Reverse bone grafting and core decompression in avascular necrosis of femoral head: Reverse bone grafting offers structural support and osteoinductive properties, facilitating bone rege

Eligibility

Inclusion criteria

Inclusion criteria: 1) Patients giving informed consent 2) Ficat and Arlet staging grade one, two and three

Exclusion criteria

Exclusion criteria: 1) Patients not willing to participate in the study 2) Ficat and Arlet staging grade four 3) Ipsilateral co morbidities or deformities affecting knee, spine or ankle 4) Any other condition affecting True Outcome analysis based on criterias included

Design outcomes

Primary

Measure	Time frame
1) Functional outcome analysis and radiological outcome analysis in Core Decompression with Reverse bone grafting 2) Functional outcome analysis and radiological outcome analysis in Core Decompression without Reverse Bone grafting 3) Comparing the outcomes of Core Decompression with Reverse Bone Grafting and without Reverse bone grafting groupsTimepoint: pre operative, 6 weeks, 12 weeks and 6 months	—

Measure

Time frame

1) Functional outcome analysis and radiological outcome analysis in Core Decompression with Reverse bone grafting 2) Functional outcome analysis and radiological outcome analysis in Core Decompression without Reverse Bone grafting 3) Comparing the outcomes of Core Decompression with Reverse Bone Grafting and without Reverse bone grafting groupsTimepoint: pre operative, 6 weeks, 12 weeks and 6 months

—

Secondary

Measure	Time frame
Functional outcome analysis and radiological outcome analysis in Core Decompression with Reverse Bone grafting enriched with biologics ( Platelet Rich plasma and Bone Marrow Aspiration Concentrate )Timepoint: pre operative, 6 weeks, 12 weeks and 6 months	—

Countries

India

Contacts

Public ContactDr Sandeep Shrivastava

Datta Meghe Institute of Medical Science and research

ceohospitals@gmail.com9765404068

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026