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A comparative study to treat Miller s class I and II Gingival recession with the help of Minimally invasive coronally advanced flap technique using Xenogenic collagen matrix in one group and Amnion-Chorion membrane in another group- A randomized clinical trial.

Comparative evaluation of root coverage obtained by MICAF technique along with Xenogenic collagen matrix vs Amnion-Chorion membrane in Miller s class I and II gingival recession - A Randomised clinical trial. - NIL

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2025/02/079944
Enrollment
28
Registered
2025-02-04
Start date
Unknown
Completion date
Unknown
Last updated
2025-03-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Interventions

Intervention1: MUCOGRAFT: a xenogenic collagen matrix of porcine origin has been developed which acts as a three-dimensional scaffold that allows the ingrowth and repopulation of fibroblasts, blood ve

Sponsors

DAMINI
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: 1. Systemically healthy individuals. 2. Individuals with age 18 or higher. 3. Individuals with good oral Hygiene compliance. 4. Presence of Miller s Class I or II gingival recession defect in atleast 2 adjacent teeth (more than 1 mm in depth). 5. Subjects who would comply with all study related procedures and will sign informed consent form.

Exclusion criteria

Exclusion criteria: 1. Non-Vital Teeth/ Active Caries 2. Subjects with active infectious diseases or who have taken antibiotics in past 3 months are on immunosuppressant drugs and/or on any medication known to cause gingival enlargement. 3. Pregnant Females and lactating mothers. 4. Subjects who are active tobacco consumers. 5. Subjects who underwent any type of periodontal surgical procedure or regenerative therapy in the past one year.

Design outcomes

Primary

MeasureTime frame
gingival recession depth (in mm), width of gingival recession at CEJ, width of keratinized gingiva (in mm), relative clinical attachment level (RCAL) (in mm), probing depth (in mm), and soft tissue thickness at baseline, 3 months and 6 monthsTimepoint: Baseline,3 months and 6 months

Secondary

MeasureTime frame
Root Coverage Aesthetic Score at 6 monthsTimepoint: 6 Months

Countries

India

Contacts

Public ContactDAMINI

ITS DENTAL COLLEGE

prashanshasharma@its.edu.in7780853231

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026