Health Condition 1: R938- Abnormal findings on diagnostic imaging of other specified body structures
Conditions
Interventions
Intervention1: Endobronchial Ultrasound-Guided Mediastinal Cryobiopsy(EBUS-MCB): All patients with undiagnosed mediastinal lesions will undergo EBUS TBNA and EBUS-MCB in the sample lymph node in the s
Sponsors
AIIMS Jodhpur
Eligibility
Inclusion criteria
Inclusion criteria: 1.Age Greater than 18 years 2.Patients with undiagnosed mediastinal lesions greater than 1 cm requiring pathology examination for diagnosis
Exclusion criteria
Exclusion criteria: 1.Age less than 18 years 2.Highly Vascular,necrotic lymph nodes and unhealthy mucosa at the site of biopsy 3.uncorrectable severe coagulation abnormalities 4.Refractory hypoxemia(sp02 less than 90% with fio2 more than 60) 5.Unstable cardiac arrhythmias,Severe Pulmonary Hypertension(RVSP greater than 50mmHg) 6.Recent MI (less than 4 weeks) or ongoing unstable angina 7.Benign/malignant stenosis of upper airway
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Safety and efficacy of Endobronchial Ultrasound-Guided Cryobiopsy in the Mediastinal lesions.Safety is determined by complications and efficacy is determined by positive biopsy resultsTimepoint: Safety at time of study(baseline) and till 2 weeks Efficacy at the time of study (baseline) | — |
Secondary
| Measure | Time frame |
|---|---|
| Yield of Endobronchial Ultrasound-Guided Mediastinal Cryobiopsy vs Endobronchial Ultrasound-guided Fine needle Aspiration Timepoint: Yield is determined by percentage of patients with positive biopsy results (After the study period) | — |
Countries
India
Contacts
Public ContactNISHANT KUMAR CHAUHAN
Aiims Jodhpur
Outcome results
None listed