Health Condition 1: E282- Polycystic ovarian syndrome
Conditions
Interventions
None listed
Sponsors
Indian Council of Medical research
Eligibility
Inclusion criteria
Inclusion criteria: Infertile women attending Gynaecology OPD and meeting the Rotterdam criteria for diagnosis of PCOS. 1 Patient with oligo or anovulation with menstrual cycle length more than 35 days 2 Patient with clinical and or biochemical evidence of hyperandrogenism with mFG score greater than or equal to 5 3 serum testosterone greater than or equal to 0.56 ng per ml 4 free androgen index greater than 5 5 Patient with Follicle number per ovary greater than 19 and or ovarian volume greater than equal to 10cc in transvaginal scan done on day 2 to 5 Those having atleast 2 criteria will be labelled as PCOS and those with anovulation criterion with Phenotype A B D will be recruited for the study Other inclusion criteria will be A Normal husband semen parameters as per WHO semen analysis 2021 criteria B Patient with atleast one patent fallopian tube confirmed by hysterosalpingography or saline infusion sonography or laparoscopy C Patient with controlled thyroid disorders and normal prolactin levels
Exclusion criteria
Exclusion criteria: 1. Patient with history of endometriosis 2.Patient is on any contraception or insulin treatment within last 3 months of recruitment 3.Patient with uncontrolled thyroid/prolactin disorder. 4.Those with history of laparoscopic ovarian drilling within last one year 5.Patient with non-classical congenital adrenal hyperplasia 6.Not willing for follow-up 7.Not having smart phone for doing online yoga classes
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Clinical pregnancy rateTimepoint: 7 weeks | — |
Secondary
| Measure | Time frame |
|---|---|
| Follicular responseTimepoint: 14 days;Ongoing pregnancy rateTimepoint: 12 weeks;early abortion rateTimepoint: 12 weeks;Live birth rateTimepoint: 9 months;Quality of life assessment using PCOSQOL-I scaleTimepoint: 0 & 24 weeks | — |
Countries
India
Contacts
Public ContactReeta Mahey
AIIMS, New Delhi
Outcome results
None listed