Health Condition 1: O009- Ectopic pregnancy, unspecified Health Condition 2: O008- Other ectopic pregnancy Health Condition 3: O002- Ovarian pregnancy Health Condition 4: O001- Tubal pregnancy
Conditions
Interventions
Intervention1: Letrozole: Name letrozole
Dose 10 MG in two divided doses
Duration Beta hCG is seen on day 4 and day 7 and if the fall is by 15 percent then weekly follow up till complete resolution.
Sponsors
Meghasriti
Eligibility
Inclusion criteria
Inclusion criteria: Ectopic pregnancy confirmed by physician. Serum beta HCG less than 3000 mIU/mL. Adnexal mass less than 35 mm with cardiac activity or less than 40 mm without cardiac activity. Patient is hemodynamically stable.
Exclusion criteria
Exclusion criteria: Intrauterine pregnancy Beta HCG more than 5000 MIU/ML Ruptured ectopic pregnancy Unruptured ectopic pregnancy with significant pain
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| To determine the resolution of ectopic pregnancy by estimating serum human chorionic gonadotropin (beta hCG) levels below 5mIU/mLTimepoint: 4th day of administration of either drug followed by 7th day of administration. If the decline between 4th and 7th day is more or equal to 15 percent then weekly monitoring of bhcg will be done till it comes down to less the 5 mIU/ml | — |
Secondary
| Measure | Time frame |
|---|---|
| To assess the changes in ovarian reserve antimullerian hormone AMH & hematologic changes (CBC, LFT)associated with the two medical treatments.Timepoint: AMH, LFT AND CBC will be recorded on the following time points 0 day- on the day of administration of either drug After 1 month After 3 months | — |
Countries
India
Contacts
Public ContactProf Dr Gitanjali Deka
Guwahati Medical College, Guwahati
Outcome results
None listed