Skip to content

Study of dietary pattern education to reduce homocysteine level and blood pressure

Effectiveness of Customized Interventions on Therapeutic Response and Quality of Life among the Adults with H hypertension attending medicine OPDs of selected hospital in Sikkim A Randomized Controlled Trial - Nil

Status
Active, not recruiting
Phases
Phase 2
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2025/02/079846
Enrollment
550
Registered
2025-02-03
Start date
Unknown
Completion date
Unknown
Last updated
2025-03-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: I10- Essential (primary) hypertension

Interventions

Intervention1: Dietary interventions: Intervention with routine care includes Individualized teaching on dietary pattern to reduce homocysteine and blood pressure level Distribution of diet plan for m

Sponsors

Sikkim Manipal College of Nursing
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: Phase 1 550 sample size Age 19-60 years willing to participate in the study Able to read and understand English Nepali language Phase 2 104 sample size Adults diagnosed to have H hypertension in phase 1 The participants will be randomized into experimental and control group 54 each in both group but it will be recalculated after the finding of the phase 1

Exclusion criteria

Exclusion criteria: Phase 1 Hypertensive adults with comorbidities such as Coronary Artery Disease Myocardial Infarction Heart Failure Heart attack Stroke Diabetes Mellitus Chronic Kidney Disease Physical and or Mental disability Adults who are under folic acid and vitamin B supplementation adults with the report of serum homocysteine level more than 15micromole per liter Phase 2 Adults with Baseline systolic BP 180mmHg and diastolic BP 110mmHg Report of serum homocysteine level more than 15micromole per liter

Design outcomes

Primary

MeasureTime frame
Serum homocysteine level and Blood pressureTimepoint: During enrollment to the study 2nd month after intervention 4th month after intervention 6th month after intervention

Secondary

MeasureTime frame
Adherence to antihypertensives Adherence to dietary practices and Quality of LifeTimepoint: During enrollment to the study 2nd month after intervention 4th month after intervention 6th month after intervention

Countries

India

Contacts

Public ContactDr Rinchen Doma Bhutia

Manipal College of Nursing Manipal Academy of Higher Education Manipal

shyli.mel@manipal.edu8095976561

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026