A clinical trial to study the effect of low dose noradrenaline infusion on neuromonitoring in patients undergoing spine surgeries

The effect of low dose noradrenaline infusion on SSEP and MEP monitoring in patients undergoing spine surgeries:A randomized controlled trial - NIL

Status

Active, not recruiting

Phases

Phase 2

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2025/02/079834

Enrollment

Registered

2025-02-03

Start date

Unknown

Completion date

Unknown

Last updated

2025-03-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: G959- Disease of spinal cord, unspecified

Interventions

Intervention1: Patients Undergoing spine surgery will receive lowdose noradrenaline or placebo according to their group: We divide patients into two groups N and S.Test drug infusion will be commensed

Eligibility

Inclusion criteria

Inclusion criteria: Diagnosed Spinal Pathology for surgery

Exclusion criteria

Exclusion criteria: Patient refusal, history of epilepsy, existing motor weakness, patients with pacemakers, renal dysfunction, respiratory dysfunction, history of stroke

Design outcomes

Primary

Measure	Time frame
To assess the effect of low dose noradrenaline on amplitude and latency of SSEP and MEP in IONMTimepoint: 18 months	—

Secondary

Measure	Time frame
To assess hypotensive episodes To assess the requirement of rescue drugs in both groupsTimepoint: 18 months	—

Countries

India

Contacts

Public ContactDR VISHWANATH BHAIRE

Yashoda hospital secunderabad

vishwasb216@gmail.com9914015533

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026