Health Condition 1: K859- Acute pancreatitis, unspecified
Conditions
Interventions
Intervention1: NA: NA
Control Intervention1: NA: NA
Sponsors
Indian Council of Medical Research
Eligibility
Inclusion criteria
Inclusion criteria: Apparently children of both sexes with acute recurrent pancreatitis
Exclusion criteria
Exclusion criteria: 1.Associated liver disorders 2.concurrent use of pancreatic enzymes, 3.cholestasis 4.diagnosed inflammatory bowel disease, 5.Diagnosed celiac disease or small bowel malabsorption 6.previous surgical intervention on the gastrointestinal tract, 7.clinical suspicion of cystic fibrosis based on history of chronic respiratory disease/recurrent lung infection and/or family history. 8.Any major illness over the last 3 months 9.Gastroenteritis in the last 1 month 10.Drugs that affect intestinal motility in the last 1 month
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| To determine the prevalence of EPI in a cohort of children with acute recurrent pancreatitis as measured by the 13C MTG breath test either at diagnosis or in follow upTimepoint: Breathes samples collected every 30 minutes for 6 hours. At the 3rd hour CO2 production measured. At 4th hour a light meal consisting of 75g of fermented legume and rice along with 25g chutney sauce given. Subsequently breath test will be repeated for 2,4 and 6 months.pancreatitis as measured by the 13C MTG breath test either at diagnosis or in follow up | — |
Secondary
| Measure | Time frame |
|---|---|
| 1.To determine the duration of recovery of EPI in ARP following an acute episode using repeated measures of the 13C MTG breath test at 2,4 and 6 months 2.To assess change in nutritional status after 12 months of PERT in children with ARP compared to baseline 3.To develop a clinical investigation to measure EPI in children using stable isotopes which is as accurate but shorter than the standard test of 6 hrs Timepoint: Breathes samples collected every 30 minutes for 6 hours. At the 3rd hour CO2 production measured. At 4th hour a light meal consisting of 75g of fermented legume and rice along with 25g chutney sauce given. Subsequently breath test will be repeated for 2,4 and 6 months | — |
Countries
India
Contacts
Public ContactShalini Gajnan Hegde
St. Johns Medical College Hospital
Outcome results
None listed