study on advanced platelet rich fibrin for treating mandibular fractures.

Evaluation of efficacy of advanced platelet rich fibrin in healing of mandibular fractures- A prospective clinical study - HEAL-PRF

Status

Active, not recruiting

Phases

Phase 2Phase 3

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2025/01/079783

Enrollment

Registered

2025-01-29

Start date

Unknown

Completion date

Unknown

Last updated

2025-03-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: S026- Fracture of mandible

Interventions

Intervention1: advanced platelet rich fibrin: Only once just after the reduction of fracture segment. prepared from 10ml patient blood Control Intervention1: fracture healing without advanced platelet

Eligibility

Inclusion criteria

Inclusion criteria: Patients requiring open reduction with internal fixation of bilateral mandibular fracture under general anesthesia. Patients who are willing and be able to provide informed consent and be available for multiple follow up visits. Patients with the age group ranging from 18-60 years.

Exclusion criteria

Exclusion criteria: Patients with any preexisting pathology. Patients with uncontrolled systemic illness. Patients who is taking Bisphosphonates drug. Interfragmentary distance between fractures more than 1 mm.

Design outcomes

Primary

Measure	Time frame
healing will be faster for mandibular fractures where we have applied Advanced-platelet rich fibrinTimepoint: post-operatively day 1 and 3 months	—

Secondary

Measure	Time frame
advanced platelet rich fibrin will be reduce swelling on applied siteTimepoint: post-operatively day-1 & day-7	—

Countries

India

Contacts

Public ContactDr Mahesh Kumar R

Sri Siddhartha Dental College

mahu017@gmail.com9845417365

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026