Health Condition 1: C00-C14- Malignant neoplasms of lip, oral cavity and pharynx
Conditions
Interventions
Intervention1: Evaluation of efficacy of Methadone for neuropathic pain in patients of head and neck malignancy.: Analgesic optimisation with methadone syrup for relief of neuropathic pain head and ne
Sponsors
Dr BRA IRCH, All India Institute of Medical Sciences,New Delhi
Eligibility
Inclusion criteria
Inclusion criteria: Age greater than 18 years and less than 65 years. Patients with head and neck malignancy having neuropathic pain who have corrected QT interval Patients who are already on stronger opioids for more than 14 days and still have pain score more than 4 on NRS.
Exclusion criteria
Exclusion criteria: Patients who have received tablet morphine for less than 2 weeks or on weaker opioids. Patients with deranged renal functions, dyselectrolytemia and abnormal ECG. Patients currently in fever. Patients not willing to apply transdermal patch.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| To compare the analgesic efficacy of Methadone and Fentanyl for neuropathic pain in head and neck malignancies.Timepoint: Patient will be evaluated at 1 week, 3 week, 5 week, 2 months and 3 months. | — |
Secondary
| Measure | Time frame |
|---|---|
| To evaluate reduction in pain after 1 week, 3 week, 5 week, 2 months and 3 months. To determine the breakthrough pain with the given medications.Timepoint: Patient will be evaluated at 1 week, 3 week, 5 week, 2 months and 3 months. | — |
Countries
India
Contacts
Public ContactDr Sachidanand Jee Bharati
All India Institute of Medical Sciences, New Delhi
Outcome results
None listed