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Comparing the efficacy of dexmedetomidine and clonidine in spinal anesthesia in infra umbilical surgeries

Effect of dexmedetomidine versus clonidine as an adjuvant to hyperbaric bupivacaine in subarachnoid block for the duration of analgesia in the patients undergoing infra umbilical surgeries - Nil

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2025/01/079724
Enrollment
100
Registered
2025-01-29
Start date
Unknown
Completion date
Unknown
Last updated
2025-03-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: O- Medical and Surgical

Interventions

Intervention1: Subarachnoid block with study drugs dexmedetomidine and clonidine: Subarachnoid block given with the dexmedetomidine and clonidine and Comparing duration of analgesia between them Contr

Sponsors

Dr Preeti Shirabur
Lead Sponsor
ESIC Medical college and PGIMSR
Collaborator

Eligibility

Inclusion criteria

Inclusion criteria: 1. Patient willing to give informed consent 2. American Society of Anesthesiologists (ASA) physical status I or II 3. Age 18-60 years. 4. Elective infra umbilical surgical procedures requiring regional anesthesia.

Exclusion criteria

Exclusion criteria: 1. BMI below 18 or above 35 kg/m2 2. Presence with known contraindications for spinal anesthesia. 3. Preoperative intake of opioid or non-steroidal anti- inflammatory drugs for chronic pain. 4. Chronic hepatic or renal failure.

Design outcomes

Primary

MeasureTime frame
duration of analgesia between dexmedetomidine and clonidine as an adjuvant to hyperbaric bupivacaine in spinal anesthesia for infra umbilical surgeries.Timepoint: 6 hrs—

Secondary

MeasureTime frame
1. To compare the onset of sensory and motor block between dexmedetomidine and clonidine. 2. To compare the duration of the motor block between dexmedetomidine and clonidine. Timepoint: 6 hrs—

Countries

India

Contacts

Public ContactPreeti Shirabur

ESIC medical College and PGIMSR

10drdeepak@gmail.com9980050864

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026