Health Condition 1: K739- Chronic hepatitis, unspecified
Conditions
Interventions
Intervention1: PATIENT AND OUTCOME ASSESSOR BLINDED RANDOMISED CONTROL TRAIL: study the adequacy of sample, fragments and complete portal tracts and histological diagnosis of the sample obtained by 1
Sponsors
None listed
Eligibility
Inclusion criteria
Inclusion criteria: 1.Patients with an indication for liver biopsy 2.Platelet count more than 50,000 3.International normalized ratio (INR) less than 1.5
Exclusion criteria
Exclusion criteria: 1.Age lessthan 18 years 2.Pregnant patients 3.Inability to obtain consent 4.Anticoagulants or anti-platelet agents use (excluding aspirin) within the last 7 to 10 days 5.Platelet count less than 50,000 6.INR morethan 1.5 7.Presence of ascites 8.Hemophilia
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| 1.Comparison of adequacy of liver biopsy specimen between 19 G EUS FNA and 19 G FNB needles with Pre processing length of longest piece more than 15 mm and CPTs more than or equal to 5 in number 2.Comparison of Diagnostic yield of liver biopsy between 19 G EUS FNA and 19 G FNB needlesTimepoint: Baseline | — |
Secondary
| Measure | Time frame |
|---|---|
| 1.Length of Longest Piece 2.Number of Participants with LLP post-processing length less than 2 cm or more than 2 cm 3.Pre-processing Aggregate Specimen Length measured in centimeter 4.Post-processing Aggregate Specimen Length measured in centimeter 5.Number of portal triads in the specimen. 6.Number of Participants with less than 11 Portal Triads or more than 11 Portal TriadsTimepoint: 23 months from January 2024 to November 2025 | — |
Countries
India
Contacts
Public ContactVvienodd Uppuv
Department of Gastroenterology, AIIMS Jodhpur
Outcome results
None listed