Health Condition 1: E282- Polycystic ovarian syndrome
Conditions
Interventions
None listed
Sponsors
Faculty of Ayurveda Institute of Medical Sciences BHU
Eligibility
Inclusion criteria
Inclusion criteria: 1)Female patients of Age group 16 - 40 years. 2)Patients diagnosed with PCOS as defined by Modified Rotterdam Criteria ie if any two of the following are present (i)Clinical(Acne, hirsutism, hairloss) or Biochemical(raised total or free Testosterone ) evidence of hyperandrogenism. (ii) Oligo-Anovulation (Oligo-amenorrhoea (cycles more than 35 days apart or less than 8 menses a year ) (iii)Polycystic Ovarian Morphology ( more than or equal to 20 follicles per ovary in either ovary, more than or equal to 10 cm ovarian volume) 3) Both married and unmarried patients
Exclusion criteria
Exclusion criteria: 1. Patient of age less than 16 and above the age of 40 years. 2. Patients with diagnosed cases of congenital malformation of uterus, adnexa or reproductive organs. 3. Benign and Malignant lesion of reproductive organs. 4. Endocrinal dysfunction like Thyroid Dysfunction, Adrenal Hyperplasia. 5. Women with chronic ailments (systemic diseases like TB, DM, jaundice, bronchial asthma, cardiovascular diseases, Chronic liver Disease etc.). 6. Patients with Anorectal disease like Haemorrhoids, fistula, fissures or having any history of psychological disorder. 7. Patient having Acute pelvic inflammatory disease. 8. Patient taking any hormonal therapy and history of Hormonal Contraception within 3 months prior to study , patient taking lipid lowering drugs or other drugs affecting Insulin Senstivity or Serum Androgen.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Normalization of certain parameters that include- 1)General Body Parameters a)BMI b)Waist Circumference c)Hip Circumference d)Waist Hip Ratio 2)Hormonal levels: A) Serum FSH on day 2 or 3 of menses B) Serum LH on day 2 or 3 of menses C) LH/FSH ratio D) Serum Prolactin E) Serum TSH F) Serum Testosterone G) Serum AMH 3) HOMA-IR 4) USG (Pelvis) Colour Doppler : Ovarian Volume Number and size of Dominant follicle Uterine Artery Resistive index 5) C-reactive protein 6) Lipid Profile 7) Clinical Hyperandrogenism ( modified Ferriman-Gallway score) 8)LFT and RFT Values Timepoint: A total of 4 follow ups at an interval of one month | — |
Secondary
| Measure | Time frame |
|---|---|
| Improvement in the quality of life of PCOS patients pertaining to their physical mental emotional social & behavioural well beingTimepoint: A standard PCOS Questionnaire will be attempted at baseline before the start of treatment & at the end of 3 months that is after the end of treatment | — |
Countries
India
Contacts
Public ContactDr Preeti Chouhan
Institute of Medical sciences Faculty of Ayurveda Banaras Hindu University
Outcome results
None listed