To compare the effect of intravenous magnesium sulphate and nebulization of magnesium sulphate on intubation response and peak airway pressures in patients undergoing laparoscopic surgeries

A comparative study of intravenous magnesium sulphate and nebulization of magnesium sulphate on attenuation of intubation response and airway pressure in patients undergoing laparoscopic surgeries, a randomized control trial. - nil

Status

Active, not recruiting

Phases

Phase 2

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2025/01/079710

Enrollment

Registered

2025-01-29

Start date

Unknown

Completion date

Unknown

Last updated

2025-03-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: K801- Calculus of gallbladder with othercholecystitis

Interventions

Intervention1: Nebulization of Magnesium Sulphate: Nebulization of Magnesium Sulphate 250mg made to 5ml by adding sterile water 10 minutes before induction of anaesthesia Control Intervention1: Intrav

Eligibility

Inclusion criteria

Inclusion criteria: Patients aged between 18 to 60 years . Patients willing to give informed written consent Patients with ASA Grade 1 and Grade 2 Patients scheduled for surgeries under general anaesthesia for laparoscopy.

Exclusion criteria

Exclusion criteria: Patients refusal to give informed written consent Patients belonging to ASA Grade 3, 4, 5 Patients with cardiovascular, respiratory, renal and hepatic derangement Patients with history of drug allergy Pregnant women Patients with anticipated difficult airway

Design outcomes

Primary

Measure	Time frame
To compare hemodynamic response after intubation.Timepoint: AT Basal, 2min, 5 min and 7 min after intubation	—

Secondary

Measure	Time frame
To compare peak airway pressures after intubation.Timepoint: At Basal , 2 min , 5 min, 7 min after intubation	—

Countries

India

Contacts

Public ContactDr Chiranthkumar G Nelogal

Bangalore Medical College and Research Institute

chiranth.nelogal@gmail.com9686325147

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026