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A comparative clinical study to see the haemodynamic responses to laryngoscopy and intubation with the use of two intravenous drugs

COMPARISION OF INTRAVENOUS LIGNOCAINE AND INTRAVENOUS DEXMEDETOMIDINE IN ATTENUATION OF HAEMODYNAMIC RESPONSES TO LARYNGOSCOPY AND INTUBATION IN CONTROLLED HYPERTENSIVE PATIENT - NIL

Status
Active, not recruiting
Phases
Phase 4
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2025/01/079690
Enrollment
156
Registered
2025-01-29
Start date
Unknown
Completion date
Unknown
Last updated
2025-03-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: O- Medical and Surgical

Interventions

Intervention1: Lignocaine: To compare the haemodynamic responses of intravenous lignocaine( 1.5mg/kg body weight)during laryngoscopy and intubation in pateint under going general anesthesia for a tota

Sponsors

Popy Borah
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: 1.Patients belonging to age group 18-65 years 2.Patients belonging to ASA grade 2 3.Written and informed consent from the study population. 3.Controlled hypertensive patient on anti hypertensive medication

Exclusion criteria

Exclusion criteria: 1.Patient with heart rate less than 60beats/minutes 2.Patient with systolic blood pressure less than 100mmhg 3.Patient with anticipated difficult intubation 4.Patient with known cardiac disease except hyprtension 5.Patient with history of renal, hepatic,cerebral disease, peripheral vascular disease, pregnant women and lactating mothers 6.History suggestive of sensitivity to drugs used in the study 7.Intubation attempts lasting more than 30seconds 8.Patient who is on beta blocker drugs as anti hypertensive medication

Design outcomes

Primary

MeasureTime frame
To compare the various haemodynamic responses in each group, namely heart rate,systolic blood pressure ,diastolic blood pressure,mean arterial pressure,oxygen saturationTimepoint: Before induction,during intubation, after 1,3,5 and 10 minutes post intubation

Secondary

MeasureTime frame
1.To compare the adverse effects (if any)of the drugs studied in each group 2.To evaluate the level of sedation at the time of induction of the patient Timepoint: At the time of induction and post induction

Countries

India

Contacts

Public ContactDr Rajib Hazarika

Gauhati Medical College and Hospital

rajibhazarika8@gmail.com9864063140

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026