Health Condition 1: L80- Vitiligo
Conditions
Interventions
Intervention1: Tofacitinib: Patients in one group will be applying 1 finger tip unit of Tofacitinib 2 percent ointment topically over vitiligo lesions for a total duration of 24 weeks once daily durin
Sponsors
Dr Kavita Swami
Eligibility
Inclusion criteria
Inclusion criteria: vitiligo patients with affected total body surface area less than 5 percent, who are equal to or older than 18 years of age not taking any systemic treatment from past 3 months
Exclusion criteria
Exclusion criteria: vitiligo patients who have only mucosal involvement, or TBSA more than 5 percent, or those requiring systemic treatment, or pregnancy or lactation, or younger than 18 years of age, or having known hypersensitivity to momatasone cream, tacrolimus ointment or tofacitinib ointment not consenting to the study
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Number and percentage of patients achieving treatment success which is defined by Vitiligo noticebility scale grade more than 3 or more than 50% repigmentation in vitiligo patch in both groups after 24 weeks of treatment. Timepoint: 24 weeks | — |
Secondary
| Measure | Time frame |
|---|---|
| 1. Number and percentage of patients achieving treatment success which is Vitiligo noticebility scale grade more than or equal to 3 or more than 50% repigmentation as per various types of vitiligo at the end of 24 weeks. 2. Number and percentage of patients who had any improvement in leukotrichia. 3. Number of patients achieving treatment success which is Vitiligo noticebility scale grade more than or equal to 3 or more than 50% repigmentation in acral and non acral vitiligo in both groups at the end of study.Timepoint: 24 weeks | — |
Countries
India
Contacts
Public ContactDr Kavita Swami
All India Institute of Medical Sciences Gorakhpur
Outcome results
None listed