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A Comparative Evaluation Of Peri-Implant Healing In Patients Using 0.12% Chlorhexidine And 0.12% Chlorhexidine Plus Hyaluronic Acid Mouthwash By Clinical And Immunological Analysis - An In Vivo Study

A Comparative Evaluation Of Peri-Implant Healing In Patients Using 0.12% Chlorhexidine And 0.12% Chlorhexidine Plus Hyaluronic Acid Mouthwash By Clinical And Immunological Analysis - An In Vivo Study - NIL

Status
Active, not recruiting
Phases
Phase 3Phase 4
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2025/01/079670
Enrollment
38
Registered
2025-01-28
Start date
Unknown
Completion date
Unknown
Last updated
2026-03-30

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: K062- Gingival and edentulous alveolar ridge lesions associated with trauma

Interventions

Intervention1: 0.12% chlorhexidine Mouthwash: Chlorhexidine is a gold standard antiseptic agent widely used in dentistry due to its proven efficacy against a broad spectrum of microorganisms. As a 0.1

Sponsors

Nil
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: Out patients at the hospital within the age group of 18-60 years. Participants who are systemically healthy. Participants requiring dental implant insertion in a single-tooth edentulous area with the presence of healthy teeth adjacent to the healed extracted site Willing and able to provide written informed consent and understand the study protocol.

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

MeasureTime frame
"The healing after the use of 0.12% chlorhexidine plus hyaluronic acid mouthwash is expected to demonstrate similar or superior clinical outcomes compared to the use of 0.12% chlorhexidine mouthwash (without hyaluronic acid) in peri-implant tissues."Timepoint: base line,6 weeks,12 weeks

Secondary

MeasureTime frame
"The cytokine (IL1) in GCF/PICF after the use of 0.12% chlorhexidine plus hyaluronic acid mouthwash is expected to reveal reduced levels compared to 0.12% chlorhexidine mouthwash (without hyaluronic acid) in peri-implant tissues."Timepoint: 18 months

Countries

India

Contacts

Public ContactDr Vineeta Gupta

Government Dental College

vinleo76@gmail.com9131144870

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Apr 4, 2026