To evaluate the effectiveness of oral clonidine as a premedication on intraoperative hemodynamic response for patients undergoing laproscopic cholecystectomy- A Single Blinded Randomised Control Study

Effectiveness of oral clonidine as a premedication on intraoperative hemodynamic response for patients undergoing laproscopic cholecystectomy- A Single Blinded Randomised Control Study - NIL

Status

Active, not recruiting

Phases

Phase 2Phase 3

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2025/01/079642

Enrollment

102

Registered

2025-01-28

Start date

Unknown

Completion date

Unknown

Last updated

2025-02-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: K80- Cholelithiasis

Interventions

Intervention1: Hemodynamic response and postoperative analgesic requirement: Premedication with oral clonidine 100mcgs versus vitamin C 1 hour before surgery to assess intraoperative hemodynamic respo

Eligibility

Inclusion criteria

Inclusion criteria: ASA grading 1 and 2 Elective laproscopic surgery under general anaesthesia. BMI less than 30kg/m2

Exclusion criteria

Exclusion criteria: Patient refusal for consent. ASA grading more than 3. BMI more than 30kg/m2

Design outcomes

Primary

Measure	Time frame
Intraoperative hemodynamic response( HR, BP, MAP, sevoflurane concentration, total vasopressors used, total amount of fluids given)Timepoint: Baseline, 1 min after intubation, 5mins after intubation, time of skin incision, at time of pneumoperitoneum, 15 mind after pneumoperitoneum, 15mins after release of pneumoperitoneum.	—

Secondary

Measure	Time frame
Postoperative analgesic requirement VAS SCORES RAMSAY SEDATION SCORETimepoint: 30 mins, 60 mins, 90 mins, 120 mins postoperative period	—

Countries

India

Contacts

Public ContactKARTIK RAJGOPAL L

Sri Ramachandra medical college and research hospital

vjram2001@yahoo.co.in9841219820

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026