Health Condition 1: A418- Other specified sepsis
Conditions
Interventions
Intervention1: Nil: Nil
Control Intervention1: E-point septal separation (EPSS): Measured using echocardiography in PLAX view at the tip of Mitral Valve in M MODE. EPSS is the minimum distance in mitr
Sponsors
Dr Anuradha Gajraj
Eligibility
Inclusion criteria
Inclusion criteria: Age more than or equal to 18 years of age admitted with sepsis in ICU meeting Sepsis 3.0 criteria. Sepsis is defined as life-threatening organ dysfunction caused by a dysregulated host response to infection. For clinical operationalization, organ dysfunction will be represented by an increase in the Sequential (Sepsis-related) Organ Failure Assessment (SOFA) score of 2 points or more. Patients with septic shock can be clinically identified by 1.vasopressor requirement to maintain a mean arterial pressure of 65 mm Hg or greater 2.serum lactate level greater than 2 mmol per litre (more than 18 mg per dL) in the absence of hypovolemia.
Exclusion criteria
Exclusion criteria: 1. Moderate to severe mitral or aortic valvulopathy 2. Prosthetic valves 3. Significant arrythmias 4. Pregnant patient 5. Inadequate ECHO image quality 6. Not willing for consent
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| To analyze MAPSE for identifying patients with left ventricular systolic dysfunction denoted by LVEF less than 50%, an absolute GLS lesser than 17% or both.Timepoint: Within 24hrs of Presentation | — |
Secondary
| Measure | Time frame |
|---|---|
| To analyze EPSS for identifying patients with left ventricular systolic dysfunction denoted by LVEF less than 50%, an absolute GLS lesser than 17% or both.Timepoint: Within 24hrs of Presentation;Comparing MAPSE and EPSS in identifying left ventricular systolic dysfunction in septic shock patients.Timepoint: Within 24hrs or presentation | — |
Countries
India
Contacts
Public ContactDr Sumit Ray
Holy Family Hospital
Outcome results
None listed