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Effects of two different doses of dexmedetomidine infusion on haemodynamic stress response, sedation and postoperative analgesia requirement in patients undergoing laparoscopic cholecystectomy.

A randomised clinical trial on the effects of two different doses of dexmedetomidine infusion on haemodynamic stress response, sedation and postoperative analgesia requirement in patients undergoing laparoscopic cholecystectomy. - NIL

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2025/01/079635
Enrollment
64
Registered
2025-01-28
Start date
Unknown
Completion date
Unknown
Last updated
2025-02-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: - Health Condition 2: O- Medical and Surgical Health Condition 3: O- Medical and Surgical Health Condition 4: O- Medical and Surgical

Interventions

Intervention1: Dexmedetomidine 0.2 mcg/kg/h: Study participants will be randomized into two groups. Intervention group receiving dexmedetomidine 0.2 mcg/kg/h infusion 15 minutes before induction of an

Sponsors

Sukanta Saha
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: 1. Patient of age group 18-65 yrs. 2. Patient with American society of Anesthesiologists (ASA) physical grade I or II.

Exclusion criteria

Exclusion criteria: 1. Patient who refused to give consent. 2. Local site infection. 3. History of allergy to study drugs specially amide group of drugs. 4. patient taking any analgesic and anticoagulant (bleeding tendencies). 5. uncontrolled cardiovascular, central nervous system, respiratory system comorbidities and kidney disorders. 6. Psychiatric patients. 7. Anticipated difficult intubation.

Design outcomes

Primary

MeasureTime frame
Haemodynamic changes (hypertension, bradycardia) and sedation effect.Timepoint: Haemodynamic changes (hypertension, bradycardia), sedation effect and sedation score (15 min, 30 min, 45 min, 60 min, 120 min).

Secondary

MeasureTime frame
Post-operative analgesia requirements.Timepoint: We will observe total analgesic requirement on patient demand in 24 hours post-operative period.

Countries

India

Contacts

Public ContactN Anita Devi

Regional Institute of Medical Sciences Imphal

dranitadevin@gmail.com8787458045

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026