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Pain reception monitoring to adjust dose of general anaesthesia without opioids in patients undergoing laparoscopic gall bladder surgery

Nociception monitoring for titration of opioid free general anaesthesia in patients posted for laparoscopic cholecystectomy - NIL

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2025/01/079634
Enrollment
46
Registered
2025-01-28
Start date
Unknown
Completion date
Unknown
Last updated
2025-02-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: O- Medical and Surgical

Interventions

Intervention1: Nociception monitoring using Quantinum nociception index (qNOX) for titration of dexmedetomidine administration in opioid free general anaesthesia: Patients undergoing laparoscopic chol

Sponsors

Maulana Azad Medical College and Associated hospitals
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: 1. ASA I & II patients

Exclusion criteria

Exclusion criteria: 1.Any Cardiac, renal, or hepatic disease. 2.Patients having acute infections or any febrile illness. 3.History of allergy to therapeutic drugs used in the study. 4.Basal mean arterial pressure (MAP) less than 60 mm Hg or greater than 120 mm Hg, basal heart rate (HR) less than 45 beats per min. or more than 120 beats per min. 5.Preoperative acute or chronic pain, peripheral or central nervous system disorders. 6.History of clearly diagnosed psychiatric disorders or other neurological conditions. 7.History of psychoactive drug use. 8.Pregnancy, lactation.

Design outcomes

Primary

MeasureTime frame
Mean total dose of Dexmedetomidine consumed intraoperatively.Timepoint: At the end of surgery

Secondary

MeasureTime frame
1. Mean total amount of propofol used intraoperatively. 2. Mean duration of the post operative analgesia. 3. Total number of episodes of intra-operative hypotension and bradycardia. 4. Post operative Recovery using Modified Aldrete score.Timepoint: 1. Mean total amount of propofol used intraoperatively 2. Time till first request of Inj PCM in the postop period by the patient 3.Total number of episodes of intra-operative hypotension and bradycardia 4. At 30 min and 2 hours postop

Countries

India

Contacts

Public ContactDr Shivani

Maulana Azad Medical College

drbhartitaneja@gmail.com9968604221

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026