Health Condition 1: O- Medical and Surgical
Conditions
Interventions
Intervention1: Nebulization of Dexmedetomidine 1mcg/kg + 0.9% NS: Single Dose of 5ml Nebulization of Dexmedetomidine 1mcg/kg + 0.9% NS for 20 minutes
Control Intervention1: Nebulization of 4% Lignocai
Sponsors
BGS Global Institute of Medical Sciences
Eligibility
Inclusion criteria
Inclusion criteria: 1.Patients willing to give informed written consent 2. American Society of Anaesthesiologists class I and II 3.Patients with normal airway on examination 4.Patients undergoing elective laparoscopic surgeries under general anaesthesia with endotracheal intubation with a duration of 2 to 4 hours are included in the study.
Exclusion criteria
Exclusion criteria: 1.Individuals with BMI more than 30 kg per meter square 2.Mallampati grading more than 2 3.Anticipated difficult intubation requiring more than 15 seconds for intubation or more than two attempts at laryngoscopy 4.Patients with allergy to Dexmedetomidine and Lignocaine 5.Taking medicines such as Beta blockers, Clonidine, Gabapentin, Pregabalin, Anti-convulsant, Anti-psychotics 6. Pregnant patients are excluded from the study.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| To evaluate the effects of preoperative nebulized Dexmedetomidine (1mcg per kg) and Nebulized Lignocaine 4% (3mg per kg) on the hemodynamic response to laryngoscopy and intubation by monitoring vitals Timepoint: Post Intubation at 1min, 3min, 5min, 10min, 15min, 30min, 45min, 60min, 90min, 120min, 150min, 180min, 210min and 240min. | — |
Secondary
| Measure | Time frame |
|---|---|
| Amount of Inj Fentanyl consumed intra-operativelyTimepoint: Post Intubation at 1min, 3min, 5min, 10min, 15min, 30min, 45min, 60min, 90min, 120min, 150min, 180min, 210min and 240min. | — |
Countries
India
Contacts
Public ContactDr Ramesh Kumar P B
BGS Global Institute of Medical Sciences
Outcome results
None listed