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A Clinical trial to study the effects of novel hydrophilic sealant and conventional sealant

Development and Comparative evaluation of Novel Hydrophilic pit and fissure sealants added nanoparticles with Conventional Hydrophilic sealants for prevention of dental caries- An Experimental and Clinical trial - NIL

Status
Active, not recruiting
Phases
Phase 2
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2025/01/079575
Enrollment
45
Registered
2025-01-27
Start date
Unknown
Completion date
Unknown
Last updated
2025-02-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: K025- Dental caries on pit and fissure surface Health Condition 2: K025- Dental caries on pit and fissure surface

Interventions

Intervention1: Formulated Hydrophilic nano sealant and Commercially available Hydrophilic sealant: Group I- Formulated Hydrophilic nano sealant(Calcium Fluoride nanoparticles were added to the hydroph

Sponsors

R Prabakar
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: 1.Bilateral mandibular first permanent molars which were fully erupted 2.Deep pits and fissures are present in these permanent molars (ICDAS II code 00). 3.Initial occlusal carious lesions involving the pits and fissures of enamel (ICDAS II code 01).

Exclusion criteria

Exclusion criteria: Patients who were medically compromised, children with developmental defects/hypoplastic molars or caries affected teeth, teeth with restorations or partially retained sealant restorations, and partially erupted teeth were excluded

Design outcomes

Primary

MeasureTime frame
change of color around the sealant, sealant retention, marginal adaptation, roughness of sealant surface, and fissure caries developmentTimepoint: At Baseline, 1 month, 3 months and 6 months

Secondary

MeasureTime frame
nilTimepoint: nil

Countries

India

Contacts

Public ContactJayashriprabakar

Saveetha Dental College

helloganz@gmail.com9884293869

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026