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Antimicrobial efficacy of Naturally derived alternatives as intracanal medicaments against Enterococcus faecalis: A Randomized Control Clinical Trial

Comparative evaluation of antimicrobial efficacy of chitosan, mangosteen and their combination as intracanal medicaments against E. faecalis: A Randomized Control Clinical Trial - nil

Status
Active, not recruiting
Phases
Phase 2Phase 3
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2025/01/079558
Enrollment
45
Registered
2025-01-27
Start date
Unknown
Completion date
Unknown
Last updated
2025-02-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Interventions

Intervention1: chitosan: Comparative evaluation of anti-microbial efficacy of chitosan as an intracanal medicament against E.faecalis for a period of seven days: an in vivo study Intervention2: mango

Sponsors

Lakshika Sharma
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: 1. Single rooted teeth with single canal 2. Non-vital teeth 3. Sufficient crown structure for adequate isolation 4. Age of patients between 18-55 years

Exclusion criteria

Exclusion criteria: Teeth with external/internal resorption 2. Calcified and curved canal 3. Teeth with immature apex 4. Pregnant women 5. Patients who do not consent to participate in study

Design outcomes

Primary

MeasureTime frame
To evaluate the antimicrobial efficacy of Mangosteen To evaluate the antimicrobial efficacy of Chitosan To evaluate the antimicrobial efficacy of mangosteen combined with chitosanTimepoint: For a period of seven days

Secondary

MeasureTime frame
To evaluate the antimicrobial efficacy of Mangosteen, chitosan and their combination against Enterococcus faecalisTimepoint: for a period of seven days

Countries

India

Contacts

Public ContactLakshika Sharma

Inderprastha Dental College and Hospital

dvaghela52@gmail.com9354941405

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026