Health Condition 1: O998- Other specified diseases and conditions complicating pregnancy, childbirth and the puerperium
Conditions
Interventions
Intervention1: Nebulization with Phenylephrine: Ultrasonic nebulization of 200 mcg phenylephrine diluted in 4 ml solution
i.e. (50 mcg/ml) at the rate of 12.5 mcg/min till the delivery of fetus
Intervention2: Nebulization with Norepinephrine: Ultrasonic nebulisation of 40 mcg norepinephrine in 4 ml solution (10 mcg/ml) a
Sponsors
All India institute of medical sciences, Patna
Eligibility
Inclusion criteria
Inclusion criteria: Pregnant women undergoing elective caesarean section under spinal anaesthesia.
Exclusion criteria
Exclusion criteria: Patient refusal, Patient Allergic or hypersensitive to phenylephrine or norepinephrine, Preterm pregnancy, Twin pregnancy, ASA III, IV patient, Preeclamptic patient, Patient undergoing emergency caesarean section
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Incidence of Post spinal hypotension after receiving prophylactic nebulised dose of phenylephrine and norepinephrine in patient undergoing elective caesarean sectionTimepoint: Till the end of the operation | — |
Secondary
| Measure | Time frame |
|---|---|
| Neonatal APGAR scoreTimepoint: At 1 mins, 5 mins; Any change in neonatal umbilical venous sampling for blood gas analysis.Timepoint: Just after delivery; Requirement of IV bolus dose of Phenylephrine (50 mcg)Timepoint: During caesarean section; Total volume of crystalloids (ml)Timepoint: During caesarean section; Any adverse events like nausea, vomiting and shiveringTimepoint: During caesarean section; Incidence of reflex bradycardiaTimepoint: During caesarean section | — |
Countries
India
Contacts
Public ContactNeeraj Kumar
All India institute of medical sciences Patna
Outcome results
None listed