Health Condition 1: N401- Benign prostatic hyperplasia withlower urinary tract symptoms
Conditions
Interventions
Intervention1: Kabab Chini (Piper cubeba Linn.): Kabab Chini will be powdered finely and filled in 750mg capsules Each patient will be given 3 gm of the test drug per day by giving 2 capsules of 750 m
Sponsors
National Institute of Unani Medicine
Eligibility
Inclusion criteria
Inclusion criteria: Male patients of age more than 40 and less than 80 years Patients with a history of LUTS (Urgency, Frequency, Nocturia, Incontinence, Weak stream, Straining, Dribbling of urine) attributable to BPH Mild (1 to 7) and Moderate (8 to 19) cases, according to IPSS PVR less than 150 ml and weight of prostate more than 20 gm as seen in USG BPH Grade I, II and III Patients willing to give their written informed consent and are able to do follow-up
Exclusion criteria
Exclusion criteria: Subjects having urinary retention (PVR more than 150 ml), hematuria, urinary tract infection, renal and hepatic impairment, urinary tract calculi, and congenital deformities of the urogenital tract or any abdominopelvic pathology other than BPH Known cases of bladder or urethral strictures, neurologic bladder dysfunction, and prostate and bladder cancer Subjects with a history of use of drugs with antiandrogenic properties and prostate surgery or other invasive procedure Subjects with uncontrolled hypertension (more than 140/90 mmHg), diabetes mellitus (RBS more than 200 mg/dl), and other systemic illness Subject with Serum PSA more than 4ng/ml
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Improvement in IPSS ScoreTimepoint: 0th, 15th, 30th and 45th days | — |
Secondary
| Measure | Time frame |
|---|---|
| Prostate size reduction as visualized in USG Reduction in PVR (Pre and Post) Improvement in Activities of Daily Living (ADL) assessed by BPH-specific QoL scaleTimepoint: 0th and 45th days | — |
Countries
India
Contacts
Public ContactDr Mohd Riyazuddin
National Institute of Unani Medicine
Outcome results
None listed