Health Condition 1: S098- Other specified injuries of head
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: age- 18-65 years both male and female patients who had sustained a brain injury with the GCS score of 4-15
Exclusion criteria
Exclusion criteria: Other pre-existing neurological disorders or prior head injury Patients with Impaired vision Haemodynamic instability that persists for more than 7 days after injury Clinical evidence of brainstem dysfunction within 7 days of admission conditions contraindicative of MRI such as implants
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| 1. Correlation between neuropsychological assessment scores and neuroimaging results 2. Relationship between structural and functional connectivity 3. Improvements in cognitive functioning post cognitive rehabilitation 4. Evidence of neuroplasticity observed through changes in brain connectivityTimepoint: Measured at Baseline (T1), 3 months (T2), and 6 months (T3) | — |
Secondary
| Measure | Time frame |
|---|---|
| 1. Resting state network activations correlated with specific cognitive domains 2. Recovery patterns based on TBI severity 3. Cognitive domains specific improvements will be observed 4. Overall cognitive & brain recovery across severity & time pointsTimepoint: Measured at Baseline (T1), 3 months(T2), 6 months(T3) | — |
Countries
India
Contacts
Sri Ramachandra Institute of Higher Education and Research