Health Condition 1: E282- Polycystic ovarian syndrome
Conditions
Interventions
Intervention1: Diet and Exercise
: Duration/Frequency of the proposed intervention: From baseline to 12 weeks
A. Dietary Intervention:
A.1 Diet Type: Low Glycemic Index Diet (LGID)
A.2 Route of Admi
Sponsors
ICMR
Eligibility
Inclusion criteria
Inclusion criteria: a) Inclusion Criteria of cases o Age 18 to 35 years old, with confirmed clinical diagnosis for PCOS with Rotterdam criteria. b) Inclusion Criteria of controls o Healthy females of 18-35 year age with BMI matched with regular menstrual cycles exhibiting no recent changes in menstrual patterns or abnormal elevations in follicle-stimulating hormone [FSH]).
Exclusion criteria
Exclusion criteria: c) Exclusion Criteria o Pregnant and/or lactating mothers o Use of hormonal birth control methods or fertility medications during the prior 3 months. o Women taking anti-seizure or anti-psychotic medications known to induce menstrual irregularity, hypolipidemic agents, antihypertensive medications, or antiaggregant/anticoagulants.. o Any medical history of conditions known to interfere with reproductive or metabolic function (besides PCOS) or bone and muscle metabolism, including diabetes mellitus, hyperprolactinemia, untreated thyroid dysfunction, premature ovarian failure, cushing disease, congenital adrenal hyperplasia, hyperparathyroidism, rheumatoid arthritis, renal disease, chronic obstructive pulmonary disease, and osteoporosis.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Prevalence of SOTimepoint: At baseline | — |
Secondary
| Measure | Time frame |
|---|---|
| The efficacy of individualised lifestyle modifications among sarcopenic obese individuals will be done after repeating the DEXA and the Inflammatory marker hsCRP, insulin resistivity HOMA-IR, lipid profile, levels of HbA1C, vitamin-D levels at 12-weeks post intervention.Timepoint: 12 weeks | — |
Countries
India
Contacts
Public ContactDr Deepali Garg
AIIMS Delhi
Outcome results
None listed