Health Condition 1: F321- Major depressive disorder, singleepisode, moderate
Conditions
Interventions
Intervention1: Multidomain Intervention: 45 min at least 5 times a week for 12 weeks. The intervention will consist of YoCogDiPP (which include 5 components namely Yoga Nidra, Cognitive Training, Diet
Sponsors
ICMR INDIAN COUNCIL OF MEDICAL RESEARCH
Eligibility
Inclusion criteria
Inclusion criteria: Age 18-55 years both genders, Diagnosis according to ICD 10 (F32.xx and F33.xx except F32.3 and F33.3) by psychiatrist, HDRS score equal to or more than 8, ongoing treatment for atleast 4 weeks or more, normal or corrected to normal vision (6/6 according to Snellen chart), normal color vision assessed by ishihara chart.
Exclusion criteria
Exclusion criteria: Any history brain secondary causes of cognitive impairment (like history of stroke, brain injury, exposure to toxins or neuroleptics, history of neurological disease, dementia, Alzheimer’s disease or any neurological illness with significant cognitive impairment). Dementia will be ruled out with MoCA score =18. Patients on any drugs other than antidepressants that can affect cardiac autonomic functions like antihistaminics, cough or cold medications, diuretics, sympathomimetics, parasympathomimetics will be excluded from the study. Any history of cardiac disease, allergy or non-acceptance of diet proposed
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Improvement in cognitive, autonomic, inflammatory markers with reduction in depression scores.Timepoint: baseline and after 4, 8, and 12 weeks | — |
Secondary
| Measure | Time frame |
|---|---|
| NILTimepoint: NIL | — |
Countries
India
Contacts
Public ContactDr Ashlesh Patil
AIIMS Nagpur
Outcome results
None listed