Health Condition 1: Q541- Hypospadias, penile
Conditions
Interventions
Intervention1: Injection.Paracetamol: Group PE (Pre-emptive group) will be given 15 mg/kg of intravenous paracetamol in 20 mL of normal saline over 5mins
15mins before induction of GA.
Control Intervention1: Injection.paracetamol: Group PV (Preventive group) will be given 15 mg/kg of intravenous paracetamol in 20 mL of normal saline after closure.
Sponsors
Jawaharlal nehru medical collage AMU
Eligibility
Inclusion criteria
Inclusion criteria: weight more than 10kgs open abdominal surgeries operation time less than 120 minutes ASA 1 and ASA2
Exclusion criteria
Exclusion criteria: 1) Refusal of patients attendant/guardian 2) psychiatric illness. 3) H/O allergy /hypersensitivity to paracetamol, NSAIDS 4) Haemodynamically unstable patients. 5) Hepatic and renal dysfunctions 6) Use of anticoagulants.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Time to first rescue paracetamol after extubationTimepoint: 1 hr, 24 hr | — |
Secondary
| Measure | Time frame |
|---|---|
| 1. Total paracetamol consumption in 24hours post surgery(mg) 2. Total number of patients requiring rescue paracetamol 3. Total number of patients requiring Break through analgesic (Ketorol) and Total Ketorol consumption(mg) 4. Pain score at 1hour in PACU and cumulative pain score at 24 hours 5. Side effects (vomiting, bleeding from site, stomach ache, hematemesis, allergy, anaphylactic reaction) 6. Parental satisfaction evaluated using a five-point Likert scale (very satisfied: 5, satisfied: 4, neutral: 3, dissatisfied: 2, and very dissatisfied: 1) Timepoint: 1hr, 24hr | — |
Countries
India
Contacts
Public ContactMushahid Raza Khan
Jawaharlal nehru Medical College,Aliagrh Muslim University
Outcome results
None listed