To compare the efficacy of dexmedetomidine versus clonidine as an adjuvants to 0.5 percentage ropivacaine under usg guidance in supraclavicular block in upper extremities surgery

to compare the efficacy of dexmedetomidine versus clonidine as an adjuvant to 0.5 percentage of ropivacaine under USG guidance in supraclavicular in brachial plexus block in upper extremity surgery - nil

Status

Active, not recruiting

Phases

Phase 4

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2025/01/079323

Enrollment

Registered

2025-01-23

Start date

Unknown

Completion date

Unknown

Last updated

2025-02-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: - Health Condition 2: O- Medical and Surgical

Interventions

Intervention1: Dexmedetomidine: 0.5mcg dexmedetomidine as an adjuvant with 0.5 percentage ropivaicaine in supraclavicular block post induction. Control Intervention1: Clonidine: 0.5mcg/kg clonidine as

Eligibility

Inclusion criteria

Inclusion criteria: 1) ASA grade I and II patients. 2)Aged between 18-60 years of either sex. 3)Patients undergoing upper limb surgery. 4)Availability of informed consent.

Exclusion criteria

Exclusion criteria: 1)Patients with ASA physical status III or more. 2)Patients with below 18 years and above 60 years. 3)Patients posted for emergency procedures. 4)Patients with major neurological, cardiac, respiratory, metabolic, renal, hepatic disease or with coagulation abnormalities. Patients contraindicated for regional technique. Patients with known allergies to the local anesthetics.

Design outcomes

Primary

Measure	Time frame
To compare the efficacy of dexmedetomidine versus clonidine as an adjuvants to 0.5% ropivacaine under usg guidance in supraclavicular block in upper extremities surgeryTimepoint: After administration of the block, comparison between the two groups of onset and duration of sensory and motor blockade, duration of analgesia will be assessed at baseline, after injection of study drug, at 5 mins, 10 mins, 15 mins, 30 mins, and 10 mins after surgery	—

Measure

Time frame

To compare the efficacy of dexmedetomidine versus clonidine as an adjuvants to 0.5% ropivacaine under usg guidance in supraclavicular block in upper extremities surgeryTimepoint: After administration of the block, comparison between the two groups of onset and duration of sensory and motor blockade, duration of analgesia will be assessed at baseline, after injection of study drug, at 5 mins, 10 mins, 15 mins, 30 mins, and 10 mins after surgery

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Secondary

Measure	Time frame
To compare the duration of analgesia of Dexmedetomidine versus Clonidine when added an adjuvants to 0.5% Ropivacaine in Supraclavicular Brachial Plexus Block Timepoint: Visual Analogue Score assessed at interval of half an hour for first 8 hours and then hourly till 24 hours. heart rate, mean blood pressure and respiratory rate were monitored every 15 minutes in first hour then every 30 minutes for further 2 hours. And then every 2 hours till the need of rescue analgesia.	—

Measure

Time frame

To compare the duration of analgesia of Dexmedetomidine versus Clonidine when added an adjuvants to 0.5% Ropivacaine in Supraclavicular Brachial Plexus Block Timepoint: Visual Analogue Score assessed at interval of half an hour for first 8 hours and then hourly till 24 hours. heart rate, mean blood pressure and respiratory rate were monitored every 15 minutes in first hour then every 30 minutes for further 2 hours. And then every 2 hours till the need of rescue analgesia.

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Countries

India

Contacts

Public ContactShilpa Sarang Kore

Dr.D.Y.Patil Medical College, Hospital and Research Centre

Shilpasale@gmail.com9767002436

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026