A clinical trial to study the ability of Photodynamic therapy in the improvement of gum problems and antibacterial action by comparing it with Scaling and Root planing in patients with Stage III Grade A periodontitis

Evaluation of efficacy of Photodynamic therapy as an adjunct to Scaling and Root Planing in patients with Stage III Grade A periodontitis - a randomized controlled split mouth study with clinico-microbiological assessment - NIL

Status

Active, not recruiting

Phases

Phase 4

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2025/01/079321

Enrollment

Registered

2025-01-23

Start date

Unknown

Completion date

Unknown

Last updated

2025-02-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: K056- Periodontal disease, unspecified

Interventions

Intervention1: Photodynamic therapy: 0.01% methylene blue activated by diode laser of 650 nm wavelength 2W power for 60 seconds inside the periodontal pocket Control Intervention1: Scaling and Root Pl

Eligibility

Inclusion criteria

Inclusion criteria: 1. Stage III grade A periodontitis: -CAL more than 5 mm -Bleeding on probing(BOP) in at least 30% of the teeth/sites -Pocket depth of more than 6 mm -Bone loss extends to the middle or apical third of affected roots -Tooth loss due to periodontitis involving no more than 4 teeth. 2. Patients ready to comply with oral hygiene measures. 3. Patients free from any systemic disease or taking drugs that affect healing.

Exclusion criteria

Exclusion criteria: 1. Patients with any known systemic diseases. 2. History of any recent infections within 6 months of study. 3. Smokers 4. Patients on any antibiotics for 3 months. 5. Pregnancy / lactation. 6. Patients with prior history of periodontal therapy within 6 months of the study. 7. Necrotizing Ulcerative Gingivitis/ Necrotizing Ulcerative Periodontitis.

Design outcomes

Primary

Measure	Time frame
Probing pocket depth changesTimepoint: At baseline and after 1 month	—

Secondary

Measure	Time frame
Gingival indexTimepoint: 1 month;Plaque indexTimepoint: 1 month;Clinical attachment levelTimepoint: 1 month;Microbial loadTimepoint: 1 month	—

Countries

India

Contacts

Public ContactDr V Krishnan

Government Dental College and Hospital, Cuddalore district

drkrish66@gmail.com9443496615

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026