FindTrial
Sign In

A Study on Quadriceps Muscle Thickness, Frailty, and Health Outcomes in ICU Patients Over 50 Years

Assessment of Quadriceps Muscle Layer Thickness trajectory and its association with Preadmission Frailty, comorbidities, and Mortality in Critically Ill Patients aged more than 50 years admitted in the ICU: A Prospective observational study. - NIL

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
CTRI
Registry ID
CTRI/2025/01/079288
Enrollment
40
Registered
2025-01-23
Start date
Unknown
Completion date
Unknown
Last updated
2025-02-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: R688- Other general symptoms and signs

Interventions

Control Intervention1: NIL: NIL

Sponsors

Father Muller Medical College
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: - Patients aged more than 50 years. - Admitted to the ICU. - Expected ICU stay of more than 96 hours.

Exclusion criteria

Exclusion criteria: - Patients who are pregnant. - Patients anticipated to have a poor prognosis or who choose to discontinue life-sustaining treatment. - Patients with amputated or injured lower limbs. - Patients with bilateral deep vein thrombosis. - Patients who stayed in the hospital for more than 5 days in the past 2 weeks. - Patients not ambulating independently before the illness leading to ICU admission (unable to walk more than 15m without stopping, with or without gait aid). - Patients with pre-existing primary systemic neuromuscular diseases (acute or chronic presentation).

Design outcomes

Primary

MeasureTime frame
Association of the change in QMLT from baseline to day 4, day 7, and at hospital discharge with frailty, co-morbidities, and mortality in critically ill patients aged over 50 years admitted to the ICU.Timepoint: At Baseline, 4th day, 7th day and at hospital discharge—

Secondary

MeasureTime frame
Association of organ supports & other outcomes (ventilator-free days, vasopressor-free days, Requirement of RRT, RRT-free days, LOS ICU, LOS Hospital) with a. Changes in QMLT (from baseline to day 4, day 7, & at hospital discharge) b. Frailty status c. Comorbidity status d. Baseline nutritional status Timepoint: At Baseline, 4th day, 7th day & at hospital discharge—

Countries

India

Contacts

Public ContactDr MANOJ KUMAR R

FATHER MULLERS MEDICAL COLLEGE HOSPITAL

vijayss87pm@gmail.com08072952625

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026