Comparing effects of two doses of a medicine dexmedetomidine on nerve block to relieve pain in people undergoing surgery of upper part of abdomen

Comparison of two doses of dexmedetomidine as adjuvants in external oblique intercostal block (EOIB) on postoperative analgesia in laparoscopic upper abdominal surgeries. a double blinded randomised controlled trial - Nil

Status

Active, not recruiting

Phases

Phase 4

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2025/01/079280

Enrollment

Registered

2025-01-23

Start date

Unknown

Completion date

Unknown

Last updated

2025-02-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: O- Medical and Surgical

Interventions

Intervention1: External oblique intercostal block with Dexmedetomidine 1mcg/kg: USG guided single shot External oblique intercostal block to be perfomed in the fascial plane between external oblique a

Eligibility

Inclusion criteria

Inclusion criteria: a) Age 18 to 70 years old b) American Society of Anesthesiology (ASA ) class 1 and 2 c) Patients undergoing laparoscopic upper abdominal surgeries

Exclusion criteria

Exclusion criteria: a) Patients who deny consent b) Presence of local infection c) Local anaesthetic allergy

Design outcomes

Primary

Measure	Time frame
Fentanyl consumptionTimepoint: Fentanyl consumption at 24 hours postoperatively	—

Secondary

Measure	Time frame
1. Pain score as measured by numerical rating scale 2. Postoperative nausea vomiting 3. Ramsay sedation scoreTimepoint: 1. Pain assessed immediately postoperatively, at 2 hours, 12 hours, 24 hours. 2. PONV assessed at immediate postoperatively & at 24 hours 3. Sedation assessed immediate postoperative & at 2 hours 4. Adverse events like bradycardia, hypotension at insufflation and in intraoperative period	—

Measure

Time frame

1. Pain score as measured by numerical rating scale 2. Postoperative nausea vomiting 3. Ramsay sedation scoreTimepoint: 1. Pain assessed immediately postoperatively, at 2 hours, 12 hours, 24 hours. 2. PONV assessed at immediate postoperatively & at 24 hours 3. Sedation assessed immediate postoperative & at 2 hours 4. Adverse events like bradycardia, hypotension at insufflation and in intraoperative period

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Countries

India

Contacts

Public ContactDr Aditi Suri

All India Institute of Medical Sciences

aditisuri19@gmail.com8800798097

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026