Effect of gradual increase in carbon dioxide pressure for abdomen insufflation on heart rate in laparoscopic abdominal surgery: A Prospective Randomised study

Effect of gradual increase in intra-abdominal pressure on bradycardia during creation of pneumoperitoneum in laparoscopic abdominal surgery: A Prospective Randomised study - NIL

Status

Active, not recruiting

Phases

Phase 2Phase 3

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2025/01/079245

Enrollment

1000

Registered

2025-01-22

Start date

Unknown

Completion date

Unknown

Last updated

2025-02-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: O- Medical and Surgical

Interventions

Intervention1: 1.Gradual Insufflation Group (Intervention):: Patients will undergo a gradual insufflation technique where the intra-abdominal pressure (IAP) is preset at 8 mmHg and then gradually incr

Eligibility

Inclusion criteria

Inclusion criteria: 1.Adult patients ( above 18 years old) undergoing laparoscopic abdominal surgery 2.ASA (American Society of Anesthesiologists) physical status I,II,III.

Exclusion criteria

Exclusion criteria: 1.Patients refusal for participation and consent

Design outcomes

Primary

Measure	Time frame
Incidence of bradycardiaTimepoint: during creation of pneumoperitoneum(T0 minute)	—

Secondary

Measure	Time frame
1.Incidence of Tachycardia 2.Incidence of Hypotension 3.New ECG Changes 4.Pharmacological Intervention required Timepoint: during creation of pneumoperitoneum(T0 minute)	—

Countries

India

Contacts

Public ContactDr Sudhansu Sekhar Nayak

AIIMS New Delhi

nayak.sudhansusekhar@gmail.com8874756836

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026