Study of effects in the presence and absence of intravenous dexmedetomidine on sensory block after spinal anesthesia with 0.5 percent hyperbaric bupivacaine in patients undergoing lower limb surgeries.

A Randomized Controlled Study To Evaluate The Effects With Or Without Intravenous Dexmedetomidine As A Pre Medication On Sensory Block Induced By Spinal Anesthesia With 0.5 Percent Hyperbaric Bupivacaine In Lower Limb Surgeries SMS Medical College Jaipur - NIL

Status

Active, not recruiting

Phases

Phase 4

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2025/01/079224

Enrollment

Registered

2025-01-22

Start date

Unknown

Completion date

Unknown

Last updated

2025-02-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: O- Medical and Surgical

Interventions

Intervention1: Spinal anesthesia in lower limb surgeries: To evaluate the effects with or without intravenous dexmedetomidine 1 mcg per kg bodyweight in 10ml 0.9% normal saline as a pre medication on

Eligibility

Inclusion criteria

Inclusion criteria: 1.Written Informed Consent 2.Age group of 18 to 50 years 3.Both genders 4.Patients of ASA Grade I and II 5.Weight of Patient 50 to 90 kg 6.Patients undergoing lower limb surgeries 7.Height of Patient more than 150 cm

Exclusion criteria

Exclusion criteria: 1.Patient with history of drug allergy to local anaesthestics 2.Patient with coagulation disorders or taking anticoagulant drugs 3.Patient on alpha 2 agonists and beta blockers 4.Patient with history of heart blocks ,heart rate less than 50 per minute and dysrhytmias 5.Patient with uncontrolled metabolic disease 6.Psychologically unstable patients with preexisting neurological deficits 7.Patient with Spinal Deformities 8.Patient not included in any other study

Design outcomes

Primary

Measure	Time frame
Mean onset and duration of sensory blockadeTimepoint: 1.0 min 2.2 min 3.4 min 4.6 min 5.8 min 6.10 min 7.25 min 8.40 min 9.55 min	—

Secondary

Measure	Time frame
Mean onset of motor blockade(minutes) Mean duration of motor blockade(minutes) Mean level of Sedation Mean of HR,SBP,DBP,MAP,SP02 Mean time for first rescue analgesia Proportion of cases with side effects / complicationsTimepoint: 1.0 min 2.2 min 3.4 min 4.6 min 5.8 min 6.10 min 7.15 min 8.20 min 9.25 min 10.30 min 11.35 min 12.40 min 13.45 min 14.50 min 15.55 min 16.60 min	—

Countries

India

Contacts

Public ContactDr Aakshi

Sawai Man Singh Medical College

dr.shriphal@gmail.com9928350391

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026