Health Condition 1: I259- Chronic ischemic heart disease, unspecified Health Condition 2: N189- Chronic kidney disease, unspecified
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: 1.Healthy or stable CKD or stable left ventricular dysfunction 2.Subjects willing to take part in the study after informed consent. 3.Subject willing to undergo FOT after informed consent.
Exclusion criteria
Exclusion criteria: 1.Inability to provide informed consent. 2.Recent hospitalization within 4 weeks. 3.Contraindication for FOT like fever, cough with expectoration, hemoptysis, chest pain, suspected viral infection 4.Subjects on bronchodilators, cough syrups on the day of FOT 5.Past or current history of chronic lung disease like COPD, Asthma , ILD
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Differences in lung mechanics in healthy, CKD and left ventricular dysfunction patientTimepoint: Single point at the end of study - 6 months | — |
Secondary
| Measure | Time frame |
|---|---|
| 1.To study resistance at 5, 10 & 20 Hz, reactance X5, small airway resistance (R5-R20), AX, Delta X5 in CKD & healthy subjects by FOT. 2.To study resistance at 5, 10 & 20 Hz, reactance X5, small airway resistance (R5-R20), AX, Delta X5 in LVD & healthy subjects by FOT 3.To compare resistance at 5, 10 & 20 Hz, reactance X5, small airway resistance (R5-R20), AX, Delta X5 in CKD with age, gender & height matched healthy controls.Timepoint: Single point study | — |
Countries
India
Contacts
Manipal Hospitals